Common ingredients in pet anthelmintics:

① Ivermectin (representative: Dog Xinbao)

② Plug/Selamectin (representative: Big Favor)

③ Pyrantel pamoate (representative: Quanxinbao, Baotatose)

④ Avermectin (representative: Embedol)

⑤ Dimethamidine (representative: the collar must be removed)

⑥ Chongchong Lin (representative: Ai Walker)

Ivermectin

Introduction (from Baidu Encyclopedia):

Ivermectin is a new broad-spectrum, highly efficient, low-toxic antibiotic antiparasitic drug. It has good killing effect on internal and external parasites, especially nematodes and arthropods. But it is ineffective against tapeworms, flukes and protozoa.

Principle of insecticide (from Baidu Encyclopedia):

The repellent effect of macrolide antiparasitic drugs on nematodes and arthropods lies in increasing the insect's inhibitory transmitter γ-aminobutyric acid [ The release of GABA), and the opening of Cl ion channels controlled by glutamate, enhance the permeability of the nerve membrane to Cl, thereby blocking the transmission of nerve signals, and ultimately nerve paralysis, causing muscle cells to lose their ability to contract, leading to the death of the parasite. .

Relationship with agricultural pesticides:

It is a derivative of avermectin

Whether it is directly used in agriculture:

Yes, but less often, and more used in aquaculture, Pet circle.

Represents anthelmintic drugs:

① Canine Xinbao: an anthelmintic drug in the body, mainly targeting the "heartworm" function ② Ivermectin injection: a commonly used injection drug in hospitals after mite infection

Note Matters:

① If dogs are given injections, they can only be injected subcutaneously, not intramuscularly, as it will cause poisoning; ② After injection, the concentration reaches the highest level in the body in the liver and adipose tissue, and is metabolized by the liver! ③ It is prohibited for those with severe liver, kidney, or cardiac dysfunction ④ Contraindicated for Collies and Shepherds; ⑤ The therapeutic dosage of this drug is very close to the poisonous dosage. If the dosage exceeds three times the therapeutic dosage, it is sufficient. Poisoning and death; ⑥ This drug is slowly absorbed, and adverse reactions usually take three days to appear; ⑦ If the two injections are too close together, it may cause backlog poisoning;

Suggestions:

Among the WeChat group friends, there was one last year or the year before. The dog passed away because of the injection of this drug in the hospital. It is not recommended to use this medicine unless it is absolutely necessary and if there is a mite problem; try to calculate the time of taking the drug as much as possible, extend it, and avoid frequent use. I personally suggest that taking Canine Heart Protection once in the past fifty days is enough to prevent heartworms. There is no need to take it every month.

Selamectin

Introduction (from Baidu Encyclopedia):

It is an avermectin antibiotic fermented by a genetically recombinant new strain of Streptomyces avermitilis. , is the first anti-animal internal and external parasite drug developed by Pfizer of the United States. It is effective against many parasitic parasites.It has a wide range of inhibitory and killing effects on insects, including fleas, scabies mites, ticks, hookworms, lice, nematodes and heartworm, etc.

Principle of insecticide (from Baidu Encyclopedia):

By interfering with insects Chloride channels controlled by body glutamate cause rapid, lethal and non-spastic neuromuscular paralysis in the parasite. Since flukes and tapeworms do not contain chloride ion channels controlled by glutamate, selamectin is ineffective against flukes and tapeworms, and can only kill some nematodes and arthropod surface parasites.

Relationship with agricultural pesticides:

A new generation of avermectin derivatives

Whether it is directly used in agriculture:

None yet

Represents anthelmintics:

Big favorite: an anthelmintic drug for internal and external use, for external use

Notes:

① There is too little research data on selamectin ② The safety level is higher than other ingredients, and the toxicity to liver and kidney is compared with other ingredients in this article Low; at high concentrations, mice will hang. No experimental research report has been found after long-term use for several years. Recommendations for the use of Dapai. It is available. It is much safer than ivermectin and avermectin, but it has an insect repellent ability. Limited, recommended for dogs who don’t often go to grass.

Pyrantel pamoate

Introduction (from Baidu Encyclopedia):

Also known as pyrantel and pyrantel, it is a synthetic broad-spectrum and highly efficient anthelmintic drug.

Principle of insecticide (from Baidu Encyclopedia):

The function is to inhibit cholinesterase, causing the muscles of the insect body to contract strongly and cause spastic paralysis; but it does not cause turmoil in the roundworms. Roundworm, hookworm, pinworm and mixed infections, hookworm is the most effective.

Whether it is directly used in agriculture:

None

Representative anthelmintics:

① Dog Xinbao: an anthelmintic drug in the body, mainly targeting the "roundworm" function ② Baotatose: roundworms for humans Anthelmintics are old drugs and are rarely used nowadays.

Notes:

① It is contraindicated in patients with acute hepatitis, acute nephritis and severe heart disease. ② People with coronary heart disease, a history of severe ulcers, or patients with fever should use with caution. ③ It is contraindicated in patients with liver insufficiency.

Recommendation:

Do not use if your liver or kidneys are not good.

Abamectin

Introduction (from Baidu Encyclopedia):

It is a widely used agricultural or veterinary bactericidal, insecticide, and acaricide. Also known as amendine.

Principle of insecticide (from Baidu Encyclopedia):

It has stomach poisoning and contact killing effects on mites and insects, but cannot kill eggs. The mechanism of action is different from that of general pesticides in that it interferes with neurophysiological activities and stimulates the release of γ-aminobutyric acid, which has an inhibitory effect on the nerve conduction of arthropods. Mite adults, nymphs and insect larvae will develop symptoms of paralysis after contact with avermectin, become inactive, stop feeding, and die after 2 to 4 days.

Relationship with agricultural pesticides:

Widely used in agricultural insecticides

Whether it is directly used in agriculture:

Yes

Representative anthelmintics:

Enbedol

Notes:

① According to China’s pesticide toxicity classification standards, avermectin is a highly toxic pesticide; ② toxic doses can cause significant damage to the liver; ③ toxic doses can cause kidney failure; ④ It lasts long in the body and is eliminated slowly; ⑤ Currently, there is no specific antidote for avermectin poisoning, and symptomatic and supportive treatment principles are usually adopted.

Recommendation:

Not recommended

Dimethamidine

Introduction (from Baidu Encyclopedia):

It is effective against harmful mites It has contact and fumigation effects and is effective against eggs, nymphs and adult mites. It is used as an acaricide in agriculture and livestock. It is a broad-spectrum formamidine-based acaricidal insecticide and is a moderately toxic acaricide.

Principle of insecticide (from Baidu Encyclopedia):

It has a variety of poisoning mechanisms, mainly inhibiting the activity of monoamine oxidase and inducing excitatory effects on the non-cholinergic synapses of the central nervous system of pest mites. Pest mites that are resistant to other acaricides are also highly active.

Relationship with agricultural pesticides:

Yes, it is mainly used to control various harmful mites on fruit trees, vegetables, tea, cotton, soybeans, sugar beets and other crops. It also has good control over psyllids. It is effective against the eggs of some lepidopteran pests. It also has a certain effect on scales, aphids, cotton bollworms, pink bollworms, etc. It can also prevent and control cattle and sheep ticks and mites. Dimethamidine can be mixed with organophosphorus, pyrethroids, abamectin and other pesticides to have a synergistic effect and expand the insecticidal spectrum.

Whether it is directly used in agriculture:

Yes

Represents anthelmintics:

The collar must be removed, external deworming, targeting ticks

Notes:

① It is poisonous to humans and animals, and there is no specific antidote for poisoning;

② There are cases of poisoning after skin contact;

③ Widely used in mite treatment in agriculture, breeding industry, and pet industry;

④ Widely used in tick treatment and prevention in breeding and pet industries;

⑤ When taking a medicated bath, it is better to have a low concentration and slow effect, rather than increase the concentration, which may cause poisoning!

⑥ After medicated bath, wash thoroughly with water;

⑦ Toxic doses can cause damage to the myocardium and liver;

⑧ The kidneys are the main place where amidine is eliminated, and high doses can cause renal failure.

Recommendations:

① Do not use medicated baths with amidine unless you have to!

② If you must use this medicated bath, go to the hospital to complete it to avoid the dog being allergic to this medicine and not being able to rescue it in time, or the wrong concentration leading to poisoning!

③ If you use a removable collar, it is not recommended to wear it for a long time. You only need to wear it when you go out when ticks are active in spring, summer and autumn, and take it off when you get home.

Imidacloprid

Introduction (from Baidu Encyclopedia):

It is a super-efficient nicotine (chloronicotine) insecticide with broad spectrum, high efficiency, Low toxicity and low residue, making it difficult for pests to develop resistance.

Principle of insecticide (from Baidu Encyclopedia):

It has multiple effects such as contact killing, stomach poisoning and systemic absorption. After the pests come into contact with the agent, the normal conduction of the central nervous system is blocked, causing paralysis and death.

Relationship with agricultural pesticides:

Widely used in agricultural insecticides

Whether it is directly used in agriculture:

Yes

Represents anthelmintic drug:

Ai Walker, an anthelmintic drug that integrates inside and outside the body

Notes:

① Overdose can cause damage to the nervous system and organ dysfunction, and in severe cases can lead to liver failure;

② After poisoning, "hepatocyte growth-promoting hormone" can be injected to help the liver recover. However, this is a medicine for human poisoning. It is unlikely to be easy to find for pet poisoning.

③ Do not use if your liver is not good

Recommendation:

There are not many applications for pet insecticide. I was actually quite surprised to find out that Aiwalker is an ingredient of wormwood.

Imidacloprid is the worm forest. This was ignored before due to translation differences.

Dogs with poor liver and kidneys and older dogs are not recommended.

PS: The detoxification of wormwood puts a lot of pressure on the liver.