Dogs must undergo vaccination and vaccination. Before vaccination, a physical examination must be done. Only healthy dogs can be vaccinated.

Physical health refers to a non-disease state, the puppy’s nose is moist and cool, and the body temperature, breathing and heart function are normal. Clinically, symptoms such as elevated body temperature, coughing, sneezing, vomiting, diarrhea, pus, urine and feces, dry nose, thick legs and other symptoms should not occur; otherwise, in an unhealthy state, the puppies may be in the incubation period of infectious diseases, and vaccination will Cause disease.

When puppies are in new environments, such as riding in a car (especially in summer) or coming to a veterinary hospital with a complex smell, their body temperature will rise slightly due to stress. Under normal circumstances, the body temperature of puppies is about 38.5°C. Before coming to the animal hospital for vaccination, measure the dog's temperature at home and clamp the thermometer on the inside of the leg for 5 minutes. You can know the true value of the puppy's body temperature and prevent sitting. After the car arrived at the animal hospital, the veterinarian did not agree to vaccinate her because her body temperature exceeded 39.0°C.

Some experienced dog owners, because they have experienced puppies dying from infectious diseases, after purchasing puppies, first inject canine five-part serum, canine two-part serum (canine distemper + canine parvovirus antibody) or Canine distemper serum, canine parvovirus monoclonal antibody, and then vaccinate the puppies with canine vaccine after 3 weeks. This approach is advisable, but it should be noted that after injecting the serum (antibody), there should be an interval of about 20 days before vaccination (antigen) . Otherwise, if the interval is too short, it will cause antigen (vaccine) and antibody (serum) reactions, making the vaccine ineffective.