Feline leptospirosis, also known as feline infectious jaundice, is an acute infectious disease caused by rat Leptospira. Clinically, it is characterized by visible mucosal jaundice, bleeding and hematuria. ​​​​​​​ The disease is often contracted by cats preying on diseased mice carrying Leptospira. The sick cat's body temperature rose to 40-41°C, its coat was rough and messy, the conjunctiva was edematous, congestion, spotting hemorrhage, and visible mucosal jaundice was edema under the jaw and abdomen. Urine that is red, dark red or orange indicates proteinuria. The prevention and treatment of this disease should mainly focus on exterminating rats all year round. Sick cats can use streptomycin at 25 mg per kilogram of body weight, once subcutaneously, twice a day, for 2-3 days; penicillin 40,000 units per kilogram of body weight, once subcutaneously, twice a day, for 2-3 days.