When golden retriever puppies are 45 days old, they need to receive the first dose of combined vaccine, which can prevent infectious diseases such as parvovirus, canine distemper virus, canine adenovirus, canine parainfluenza, canine leptospirosis, etc., at an interval of 21 to On the 28th day, the second dose of the combination vaccine was injected, for a total of 3 injections. After the golden retriever puppies are 3 months old, they can be injected with a vaccine to prevent rabies, and then a booster injection of a combination vaccine and a rabies vaccine every year. Since the immune system of golden retriever puppies needs a period of time to "recognize" the virus, and it takes at least three times to "remember" the virus, injection distances that are too close or injection times that are too few will affect the effectiveness of the vaccine. After the third dose of vaccine is completed, golden retriever puppies can be vaccinated against rabies.

Precautions for vaccination of golden retriever puppies:

1. Go to a regular pet hospital for vaccination and do not buy vaccines online.

2. Dogs can be vaccinated only if they are healthy and have no disease.

3. Female dogs that are pregnant or have just given birth are prohibited from being vaccinated.

4. After vaccination, you must observe for 20 minutes before going home to ensure that there are no allergic symptoms such as itching all over the body and shortness of breath.

5. Golden retriever puppies should be re-vaccinated regularly every year after they reach adulthood.

6. Dogs are very weak after being vaccinated and may experience vomiting and diarrhea. They usually return to normal in about two days. Owners should not be overly nervous. At the same time, please do not bathe your dog during this period.