What should I do if my dog ​​has uremia?

Dec 27,2023
3Min

Hospital treatment plan for dog uremia:

1. General treatment. Administer sodium bicarbonate according to the degree of acidosis (detection of plasma carbon dioxide binding capacity), and select calcium-free infusions to adjust hyperkalemia. Supplement a large amount of amino acids, high-energy, vitamin preparations, etc. to improve hyperazotemia

2. Adopt peritoneal dialysis. When blood urea nitrogen is 100 mg/100 ml, serum creatinine is 10 mg/100 ml, and serum potassium is 6 mmol/l, peritoneal dialysis can be performed.

3. Intermittent peritoneal perfusion method: the abdominal wall is clipped and disinfected, punctured with an ascitic trocar, and a multi-hole cannula is inserted. Remove the cannula and leave the cannula in place. After the perfusate is warmed, 50 to 150 ml/kg is injected each time. After staying for 40 minutes, the fluid is drained naturally and repeated 2 to 3 times. The perfusate is usually sodium lactate compound preparation.

4. When dogs have severe pulmonary edema, use a compound preparation of glucose and sodium lactate with high osmotic pressure.

Factors for dogs suffering from uremia:

1. Absorption of intestinal toxic substances, such as phenol, tyramine, phenylethylenediamine, etc., are absorbed from the intestine. After bleeding, due to kidney failure and reduced liver detoxification function, poisons accumulate in the blood and cause poisoning.

2. Due to renal failure, urea enters the intestinal cavity and is decomposed by intestinal bacteria into ammonia and ammonium salts, which are then absorbed into the blood, causing symptoms of nervous system poisoning.

3. The accumulation of toxic products from the decomposition of certain proteins, such as guanidine compounds, can inhibit the activity of certain enzymes (lactate dehydrogenase, ATPase, etc.) in the body, causing convulsions in dogs, and can also induce convulsions in dogs. Gastroenteritis, pericarditis, bleeding and reduced immune function.

4. Acidosis occurs due to impairment of excretion of acidic metabolites, causing changes in respiratory and cardiovascular activities and coma.

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